朱翻译
我写的双语小说《好运的代价》Ther Cost of Fortune“认知功能改善评分（ADAS-Cog）平均提升4.2点，p<0.001。” 陈伟低声念出最关键的一项，声音在安静中格外清晰。他在记忆中搜索同类药物的历史数据。这个提升幅度，在阿尔茨海默病二期临床中，堪称“突破性”。过于突破性了。近期类似机制药物的二期结果，平均提升在1.5-2.5点之间。4.2？这好得不真实。“Cognitive function improvement score (ADAS-Cog): average increase of 4.2 points, p<0.001.” Chen Wei read the most critical line aloud, his voice cutting through the silence. He scoured his memory for historical data on comparable drugs. This level of improvement in a Phase II Alzheimer’s trial would be considered a “breakthrough.” Too much of a breakthrough. Recent Phase II results for drugs with similar mechanisms had shown average improvements between 1.5 and 2.5 points. 4.2? It was too good to be true.
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